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Director, Bioinformatics Core
Boston, MassachusettsOrganization Facility: Beth Israel Deaconess Medical Center Category: Clinical Data Job ID: 47362BR_BIDMC Date posted: 10/01/2022
When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives.
Work Shift:Day (United States of America)About us: The BIDMC Bioinformatics Core (BBC) is part of the Precision RNA Medicine Core at Beth Israel Lahey Health. The BBC will be tightly integrated with the ‘Omics cores at BIDMC. It is the center for bioinformatics research expertise at BIDMC. We work directly with biomedical scientists across our Network and the Harvard community to implement best practice for analysis, interpretation, visualization, and dissemination of scientific discoveries using high dimensional data. The BBC team focuses on teamwork and we provide a supportive learning environment.
About you: You understand the growing need for data driven research. You have a solid track record in bioinformatics service provision, excellence in communication skills and written and verbal reporting. A thorough knowledge of current and upcoming developments in analysis of high dimensional data, genomics and the current developments in bioinformatics are essential. Management skills should be evident, with a particular focus upon project management, the ability to define specific project requirements and to execute upon specifications. Evidence of having managed developers is of value. Publications should reflect a collaborative approach – with diversity of subjects being of interest. You should be able to articulate the vision of the program, and must be able to work independently. You are not shy of taking on core projects where you provide direct consulting, or work with teams to provide consulting to biomedical researchers.
Your background is in biomedical/quantitative science with evidence of strong interest in working with researchers in diverse areas of biomedical research. You thrive on scientific challenges, enjoy collaborating with an interdisciplinary team and excel at communicating and coordinating between computational and wet-lab scientists. Learning and applying new methods is natural for you, and you are motivated to continuously expand your skills. You have superb data and project management skills. Working on different projects and deadlines, frequently in collaboration with other Cores and research groups, does not intimidate you.
Job Summary: The Bioinformatics Core Director will have strategic and tactical responsibility for the operations of the core, consultation, recruiting, overseeing core support staff and provision of leadership in developing core resources and providing research support and training for research faculty and staff at BIDMC.
The Core Director will lead a team that develops and applies bioinformatics workflows for standard and custom data analysis across a broad range of technologies, such as single nuclei sequencing, spatial transcriptomics, genome variant analyses, transcriptomics or epigenomics. The Core Director is expected to create deliverables that could serve as standards for quality and innovation in broader communities, building informatics tools for data management, omics and imaging analyses within the reality of clinical data integration.
The team will support researchers across the research community with their data management, quality control, analysis of data and presentation of results and will also be expected to coordinate selected research or support projects and act as an independent point of contact for researchers.
1. Determine BIDMC needs and work with core Scientific Directors in setting strategic, scientific and operational priorities.
2. Provide best practice bioinformatics services to investigators across campus, including pre-experiment/grant consulting, application and training on the use of bioinformatics core software tools, and integration of user-generated and large-scale public data sets.
3.Develop staffing plans and oversee recruitment; oversee developers as necessary, provide management of database design, interface design and information processing.
4. Co-ordinate a monthly seminar series, special trainings and mini-courses and organize user groups for bioinformatics related activities.
5. Develop and promote the funding model for expansion and sustainability of the core, including investments from organizational units around the community, charge-back models and collaborative grant applications to ensure long term sustainability.
6. Lead and collaborate on grant applications related to bioinformatics core projects.
7. Enable implementation of scalable workflows to disseminate analytical advances to the research community.
8. Engage with the community to both embrace and develop best practice.
9. Participate in leading national and international efforts aimed at establishing best practices and standards for omics basic science and potentially integration with clinical data representation and analysis.
10. Has full responsibility for planning, monitoring and managing department budget.
Master's degree required; Doctoral degree preferred.
5-8 years related work experience required and 5-8 years supervisory/management experience required
Demonstrated excellence in analytical, writing, and communication skills; A commitment to providing bioinformatics support for a broad range of scientific projects; Experience in developing and managing projects and people.
Extensive knowledge of public domain bioinformatics data sources, public sequence databases, genomics tools, single cell analyses, and gene expression analysis.
Evidence of software development experience and proficiency in scripting; Experience with SQL or other relational database systems, Unix and mixed operating systems environments, high-dimensional data management and analysis;
Proficient in R and Bioconductor.
Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases.
Decision Making: Ability to make decisions that are guided by general instructions and practices requiring some interpretation. May make recommendations for solving problems of moderate complexity and importance.
Problem Solving: Ability to address problems that are varied, requiring analysis or interpretation of the situation using direct observation, knowledge and skills based on general precedents.
Independence of Action: Ability to set goals and determines how to accomplish defined results with some guidelines. Manager/Director provides broad guidance and overall direction.
Written Communications: Ability to communicate complex information in English effectively in writing to all levels of staff, management and external customers across functional areas.
Oral Communications: Ability to verbally communicate complex concepts in English and address sensitive situations, resolve conflicts, negotiate, motivate and persuade others.
Knowledge: Ability to demonstrate in-depth knowledge of concepts, practices and policies with the ability to use them in complex varied situations.
Team Work: Ability to lead and direct multiple collaborative teams for large projects or groups both internal and external to the Medical Center and across functional areas. Results have significant implications for the management and operations of the organization.
Customer Service: Ability to lead operational initiatives to meet or exceed customer service standards and expectations in assigned unit(s) and/or across multiple areas in a timely and respectful manner.
Physical Nature of the Job:
Sedentary work: Exerting up to 10 pounds of force occasionally in carrying, lifting, pushing, pulling objects. Sitting most of the time, with walking and standing required only occasionally