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Genomics Bioinformatician - CardioVascular Institute

Boston, Massachusetts

Organization Facility: Beth Israel Deaconess Medical Center Category: Medical/Clinical Research Job ID: JR47974 Date posted: 03/27/2024
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Job Type: Regular

Time Type: Full time

Work Shift: Day (United States of America)

FLSA Status: Exempt

When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives.

We are seeking a skilled Bioinformatician to join our team, focusing on the integration of genomics with other omics sciences, including metabolomics and proteomics. The ideal candidate will possess a strong foundation in bioinformatics, with a proven track record of analyzing and interpreting complex biological data sets including the ability to conduct genome wide association studies, colocalization, fine mapping etc... Proficiency in programming languages such as R/ Python is essential, along with experience in using genetic analysis tools like PLINK, GCTA etc... The candidate should have experience in integrating diverse omics data sets and an understanding of genetic data analysis, bioinformatics pipelines, and statistical modeling. Strong analytical skills, the ability to work collaboratively in a multidisciplinary team, and a keen interest in advancing the understanding of complex biological systems are crucial.

Job Description:

Primary Responsibilities:

  • Assists in the design, development and maintenance of data collection instruments, databases and procedure manuals. Designs, implements, and performs data management and quality control procedures as necessary for routine and special projects. (essential)

  • Writes computer programs to combine data from separate computer files to allow comparison of data from different sources. Support the creation applications in support of research projects. (essential)

  • Collaborates with program staff on the design and analysis of biostatistics aspects of research protocols. Participates in the design of questionnaires and interview forms. (essential)

  • Analyzes data beginning with univariate and multivariate analyses such as logistic regression and factor analysis for research studies. Supports the interpretation and assist in the creation of study results in collaboration with faculty members, epidemiologists, biostatisticians and other team members. (essential)

  • Provides tabular and graphic summaries of analyses in a form suitable for inclusion in manuscripts for publication in peer reviewed scientific journals as well as for presentation at scientific meetings. (essential)

  • Travels to project specific administrative and or national clinical meetings and presents findings. Attends project team meetings as needed. (essential)

Required Qualifications:

- Master's degree in Computational Biology, Bioinformatics, or related field required; Doctoral degree preferred.

- 3-5 years related work experience required.

- Demonstrated ability to integrate multiple complex datasets including RNA-Seq transcriptional profiles, ChIP-Seq and whole genome methylomes. Must be able to apply existing algorithms in the analysis of such data and, if necessary, derive novel programs.

- Ability to conduct and interpret multivariable regression analysis, ChIP peak calling, computational motif finding and other whole genome analyses.

- Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases.


Decision Making: Ability to make decisions that are guided by precedents, policies and objectives. Regularly makes decisions and recommendations on issues affecting a department or functional area.

Problem Solving: Ability to address problems that are highly varied, complex and often non-recurring, requiring staff input, innovative, creative, and Lean diagnostic techniques to resolve issues.

Independence of Action: Ability to set goals and determines how to accomplish defined results with some guidelines. Manager/Director provides broad guidance and overall direction.

Written Communications: Ability to summarize and communicate in English moderately complex information in varied written formats to internal and external customers.

Oral Communications: Ability to comprehend and converse in English to communicate effectively with medical center staff, patients, families and external customers.

Knowledge: Ability to demonstrate in-depth knowledge of concepts, practices and policies with the ability to use them in complex varied situations.

Team Work: Ability to act as a team leader for small projects or work groups, creating a collaborative and respectful team environment and improving workflows. Results may impact the operations of one or more departments.

Customer Service: Ability to provide a high level of customer service to patients, visitors, staff and external customers in a professional, service-oriented, respectful manner using skills in active listening and problem solving. Ability to remain calm in stressful situations.

Social/Environmental Requirements:

Work requires periods of close attention to work with out interruption. Concentrated effort of up to 4 hours without break may be required.

Work is varied every day and the employee needs to be adaptable to respond to these changes and use independent judgment and manage priorities.

Potential exposure to adverse environmental conditions

  • Daily:  Exposure to dust, gas, fumes, steam, chemicals. Potential exposure to infectious diseases and/or airborne pathogens, Potential exposure to infectious diseases and/or bloodborne pathogens.

Health Care Status:  NHCW: No patient contact.- Health Care Worker Status may vary by department.

As a health care organization, we have a responsibility to do everything in our power to care for and protect our patients, our colleagues and our communities. Beth Israel Lahey Health requires that all staff be vaccinated against influenza (flu) and COVID-19 as a condition of employment. Learn more about this requirement.

More than 35,000 people working together. Nurses, doctors, technicians, therapists, researchers, teachers and more, making a difference in patients' lives. Your skill and compassion can make us even stronger.

Equal Opportunity Employer/Veterans/Disabled

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Why join Beth Israel Lahey Health?

If you’re looking for a career where you can make a difference and explore your potential, Beth Israel Lahey Health is the place you belong. Our system includes a network of hospitals, physician practices, outpatient centers, and other healthcare facilities and we offer a broad range of careers in direct patient care, environmental services, registration, finance and many other fields. We are focused on providing compassionate and personalized healthcare with a strong reputation for clinical excellence and research and offer diverse opportunities for career growth and development. Conveniently, we have many locations in communities across Eastern Massachusetts and Southern New Hampshire.

At Beth Israel Lahey Health, we see you for all that you are – your experience and your dreams. Explore our open opportunities and find out why so many have already chosen to join our team.

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